Clone: GM011
Host clonality: mouse monoclonal
Control tissue: colon, tonsil
Staining pattern: nuclear
Regulatory status: IVD, FDA Class I
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Product code:
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60-0079-7 7mL RTU
61-0079 1mL concentrate
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This antibody labels the MutL homolog 1 (MLH1) protein in the nucleus of normal proliferating cells in both normal and neoplastic tissues and does not stain colon adenocarcinoma with complete loss of MLH1 expression. MLH1 is a useful tool for classifying tumors of the gastrointestinal tract, including associated extra colonic cancers such as endometrial and prostate cancers, when used in a panel of antibodies.